The diseases that are treated using the cord blood are categorized under the following:
- l Experimental treatments
- l Therapies from clinical trials
- l Standard therapies
- Cord Blood storage and banking
Before you are to choose the correct cord blood banking, it is highly significant that you identify between the two treatment modes:
- l Autologous – the patient gets their very own stem cells
- l Allogenic – the patient gets stem cells that match from a donor, either unrelated or a sibling
When parents decide on donating the cord blood to the public bank, they are considered the supporting parents that are searching for the Allogeneic donor, an unrelated one. When the parents save the cord blood into the family bank, it means reserving their options that the baby can use its stem cells for the Autologous treatment or with the immediate relative can use them for the Allogeneic treatment.
Standard Therapies and Stem Cell Storage
Such diseases in which it transplants the blood-forming stem cells are considered the standard treatment. In some diseases, they are only seen as therapy, while with other diseases they are only considered in a situation wherein the front-line therapies are unsuccessful or when the disease turns aggressive.
Who uses the cord blood treatment?
Sometimes people are confused as to who can use the cord blood treatment. Based on the categories above, it should clear up what you need. Could it be you need the stem cell from the baby or a sibling? It can be both, yet it entirely depends on which condition is going to be treated. It will ultimately lie on the decision of the physician.
Majority of the diseases that are on the list of proven treatment are under the inherited genetic diseases. Usually, such treatments need a donor transplant, like from a sibling. According to research, it showed that the treatments that use cord blood coming from a member of the family have twice success rate as the treatment that is coming from a relative. You can find a lot of records of this from clinics that have already conducted cord blood transplant.
If you are going for the autologous use, this is when the child will get access to the cord blood stem cells storage that are in perfect match with their DNA. Some cancers of the neuroblastoma are considered the autologous treatments. The ongoing clinical trials are utilizing the stem cells of the child that are used for treating cerebral palsy and autism.
How it Save Lives
As it was introduced, cord blood stem cells are used for treating almost 80 various diseases, including inherited metabolic disorders, malignancies, deficiencies in the immune systems and anemias. Majority of the cord blood transplants have already been performed on patients that are below 18 years of age. Because of the advancement of the regenerative medicine, it is now foreseeable that individuals of any age get to benefit the therapy as mentioned above soon. The cord blood’s source that is used in the transplants can either be allogeneic or autologous.
A complication linked with the stem cell therapy, the graft-vs-host disease, happens less frequently when using the cord blood stem cells compared to any other stem cells types. It is even much rarer when the cord stem cells are from the family member, the one related to the patient.
The cord blood treatment is widely used in the following diseases:
- l Acute Leukemia, Chronic Leukemia, and Myelodysplastic Syndromes, which is often referred to as pre-leukemia
- l Lymphomas, like the Non-Hodgkin’s and Hodgkin’s Lymphoma
- l Others that are associated with blood cell proliferation like anemia, Inherited Platelet Abnormalities, Inherited Red Cell Abnormalities, Inherited Immune System Disorders, Myeloproliferative Disorders, Phagocyte Disorders and Bone Marrow Cancers
- Parents looking to store their umbilical cord blood